det er da lige nøjagtigt det jeg kan. ved godt at amidet er en del mere resistent over for hydrolyse end f.eks. estere, men amidet kan jo syrehydrolyseres. og siden det har været opbevaret ved pH 4 så jeg har god grund til at tro at en del af det er blevet nedbrudt over de 3,5år det var været opbevaret. men ja temperaturen har også en del at skulle have sagt, men der kan man jo altid bare regne hastighedskonstanten om svarende til dem temp. man er interesseret i

There are two sensitive aspects of its structure. The position of the carboxamide attachment, the 8-position, is affected by basic, or high pH, conditions. Through a process called epimerization, this position can scramble, producing isolysergic acid diethylamide, or iso-LSD. This product is biologically inactive, and represents a loss of a proportionate amount of active product. A second and separate point of instability is the double bond that lies between this 8-position and the aromatic ring. Water or alcohol can add to this site, especially in the presence of light (sunlight with its ultraviolet energy is notoriously bad) to form a product that has been called lumi-LSD, which is totally inactive in man. Oh yes, and often overlooked, there may be only an infinitesimal amount of chlorine in treated tap water, but then there is only an infinitesimal amount of LSD in a typical LSD solution. And since chlorine will destroy LSD on contact, the dissolving of LSD in tap water is not appropriate.