jeg har undret mig lidt over at når man læser synteseforskrifter (både ulovlige og lovlige) så der næsten altid at man skal vacuum destillere, men er der nogen forskel på at destillere under reduceret tryk og så destillere ved atmosfærisk tryk og så tilsvarende højere temperatur?

mit spørgsmål gik mere på hvorfor vacuum destillation er at fortrække frem for bare at hæve temperaturen

Laboratory-scale vacuum distillation is used when liquids to be distilled have high atmospheric boiling points or chemically change at temperatures near their atmospheric boiling points.[1][2][3] Temperature sensitive materials (such as beta carotene) also require vacuum distillation to remove solvents from the mixture without damaging the product. Another reason vacuum distillation is used is that compared to steam distillation there is a lower level of residue build up. This is important in commercial applications where temperature transfer is produced using heat exchangers.