Hvilken tråd var det jeg gav dig "science bitch" argumentet?
Nu vil jeg jo gøre det dejlig let og overkommeligt med et par erfaringer som folk har oplevet med 5-htp.
Men nu vi går i små sko vil jeg da gerne bakke mit argument op med mere videnskabelige artikler.
http://www.webmd.com/vitamins-supplemen ... Name=5-HTPCitat:
5-HTP SIDE EFFECTS & SAFETY
5-HTP is POSSIBLY UNSAFE for use. There is concern that it can cause a serious side effect called eosinophilia myalgia syndrome. Some people think this side effect is only caused by a contaminant in some 5-HTP products; but there is not enough scientific evidence to know if it is caused by 5-HTP, a contaminant, or some other factor. Until more is known, 5-HTP should be avoided.
Other potential side effects of 5-HTP include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems.
Special Precautions & Warnings:
Pregnancy and breast-feeding: 5-HTP is POSSIBLY UNSAFE in pregnancy and breast-feeding. Avoid using it.
Down syndrome: There are reports of 5-HTP causing seizures in some people with Down syndrome. In one group studied, 15% of people with Down syndrome receiving long-term 5-HTP treatment experienced seizures.
http://www.altmedrev.com/publications/3/4/271.pdfCitat:
Drug-Nutrient Interactions
Although no specific reports have been
published, it is possible that 5-HTP, when
taken in combination with either a selective
serotonin reuptake inhibitor (SSRI) antidepressant such as fluoxetine (Prozac), paroxetine
(Paxil), sertraline (Zoloft), or fluvoxamine
(Luvox), or an MAOI antidepressant such as
phenelzine (Nardil) or tranylcypromine
(Parnate) may cause a condition known as serotonin syndrome.56 This syndrome has been
reported in patients taking LT at doses above
1200 mg/day along with MAOIs, but was not
identified in a 12-month study with 5-HTP
(200 mg/day) taken in conjunction with an
MAOI drug.36
Serotonin syndrome is characterized
by agitation, confusion, delirium, tachycardia,
diaphoresis, and blood pressure fluctuations.
Should serotonin syndrome be suspected, 5-
HTP and any other precipitating drug (SSRI
or MAOI) should be discontinued immediately. Because of the possibility of serotonin
syndrome, 5-HTP should probably not be used
in patients currently being treated with eitheran SSRI or MAOI antidepressant. If it is used
in conjunction with either of these prescription drugs, e.g. short-term dual therapy while
changing over from an SSRI to 5-HTP, the
practitioner and patient should be aware of the
potential symptoms of this condition.
Contraindications
One additional concern regarding 5-
HTP is the possibility of an eosinophilia-myalgia syndrome (EMS) similar to the illness
linked to contaminated LT. The contamination
identified in certain batches of LT has been
related to production methods using bacterial
fermentation and subsequent inadequate filtration. This is unlikely to occur with 5-HTP,
since it is produced by extraction from plant
sources. Two cases of EMS-like symptoms
have been described in patients taking 5-HTP.
One case reported in 1980 involved the use of
very high doses (1400 mg daily).57 Because
contamination of LT was not identified as a
factor in EMS until 1990, the product consumed by this patient was not tested for contamination. The second case involved a mother
and two children who were confirmed to have
taken contaminated 5-HTP.58
Because of the possibility of serotonin syndrome (see above), 5-HTP should be
used with caution in patients currently being
treated or who have recently been treated with
either an SSRI or an MAOI antidepressant.
There are no adequate, well-controlled
studies on the use of 5-HTP in pregnancy,
therefore, it should not be used while pregnant.
Side Effects
Some patients may initially experience
mild nausea when taking 5-HTP. This effect
is usually transitory, and is best dealt with by
initiating therapy at low doses (50 mg three
times daily) and increasing the dosage gradually if necessary.
http://www.umm.edu/altmed/articles/5-hy ... 000283.htmCitat:
Precautions:
Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of your health care provider.
Tryptophan use has been associated with the development of serious conditions, such as liver and brain toxicity, and with eosinophilic myalgia syndrome (EMS), a potentially fatal disorder that affects the skin, blood, muscles, and organs (see "Overview" section). Such reports prompted the FDA to ban the sale of all tryptophan supplements in 1989. As with tryptophan, EMS has been reported in 10 people taking 5-HTP.
Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, it is possible that serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop. Always talk to your health care provider before taking higher-than-recommended doses.
People with high blood pressure or diabetes should talk to their doctor before taking 5-HTP.
If you take antidepressants, you should not take 5-HTP (see "Possible Interactions" sections).
People with liver disease, pregnant women, and women who are breastfeeding should not take 5-HTP.
Source: 5-Hydroxytryptophan (5-HTP)
http://www.umm.edu/altmed/articles/5-hy ... z2VMLYZKU2 University of Maryland Medical Center
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