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Hyoscyamin

Uses
Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in palliative care.[1] It may be useful in pain control for neuropathic pain treated with opioids as it increases the level of analgesia obtained. Several mechanisms are thought to contribute to this effect. The closely related drugs atropine and scopolamine and other members of the anticholinergic drug group like cyclobenzaprine, trihexyphenidyl, and orphenadrine are also used for this purpose. When hyoscyamine is used along with opioids or other anti-peristaltic agents, measures to prevent constipation are especially important given the risk of paralytic ileus.

[edit] Side effects
Side effects include dry mouth and throat, eye pain, blurred vision, restlessness, dizziness, arrythmia, flushing, and faintness. An overdose will cause headache, nausea, vomiting, and central nervous system symptoms including disorientation, hallucinations, euphoria, sexual arousal, short-term memory loss, and possible coma in extreme cases. Some people can experience transient combativeness. The euphoric and sexual effects are stronger than those of atropine but weaker than those of scopolamine, as well as dicycloverine, orphenadrine, cyclobenzaprine, trihexyphenidyl, ethanolamine antihistamines like phentyltoloxamine and the like

10 mg of hyoscyamine is the minimum reported lethal dose in humans. So be careful.

I wouldn't take any more than 1 mg if I were you. SWIM uses hyoscyamine all the time to potentiate the effects of mescaline and other psychedelics, but he uses doses of 100 micrograms or so, usually as Datura stramonium seeds (2-5 seeds usually). Messing around with doses above 1 mg is really asking for trouble. With 10 mg being a possible lethal dose, albeit the minimum, you’re really getting into a dangerous area.

If you take much more than 1.5 mg, you can experience delirium. The delirium can be so bad that you have no idea if what you’re seeing is real or not, and your memory is extremely short so you might forget you took the pills, and then take more, and then more, and then more and then die. It messes with your short term memory.

Actually though, scopolamine is more dangerous mentally than hyoscyamine is. The delirium produced by scopolamine is much worse. Either way, delirium is a very dangerous state to be in.

Hyoscyamine is a great anti-nausea medicine and potentiator of other psychedelics when used in safe doses. But when toying around with it to produce delirium, you’re getting close to the lethal dose. Delirium is considered a sign of overdose, and the medical community is NOT joking about that. Delirium is a warning sign that you might be about to die. Delirium happens right before a lethal dose is taken.