niks... Det er Ibotainsyren der giver det body high som opleves i starten inden den psykedeliske effekt tager over. Det er dog forbundet med et betydeligt bodyload.
http://leda.lycaeum.org/?ID=16074Preparation and Ingestion
"The most important aspect of Amanita muscaria preparation lies in the drying and/or of heating of the mushroom. What these two processes do is convert the less powerful Ibotenic acid into the highly psychopharacologically chemical muscimol through decarboxylation. If this is not done then the potency as an inebrient is lessened."
Jeg kan ikke finde min første kilde til det med temperaturen men jeg har fundet andre kilder som siger at de skal tørres ved 75-85 grader. Giver også meget godt mening da Muscimol smelter ved 175 fahrenheit = 80 grader celcius.(ifj. erowid) Ibotainsyre ved 62-66 grader.
http://www.erowid.org/plants/amanitas/amanitas_chemistry.shtmlJeg skrev forkert i mit første indlæg. Har researchet lidt mere. Det er hovedsageligt Ibotainsyre som bliver udskilt i urinen. Ca. 15% bliver omdannet til muscimol efter indtagelse, resten bliver udskilt i urinen. Kun 1/3 af Muscimolen bliver udskilt i urinen, 1/3 oxiderer, og 1/3 bliver metaboliseret videre til et ikke psykoaktivt derivant. Det er Ibotainsyren som giver følelsen af lethed og muskelspændingerne i første del af trippet.
http://www.erowid.org/plants/amanitas/amanitas_info_ott.shtml"EFFECTS OF IBOTENIC ACID AND MUSCIMOL
Ibotenic acid evokes entheogenic effects in human beings at doses ranging from 50 - 100 mg (Chilton 1975; Theobald et al. 1968). An equivalent effect is produced by 10-15 mg of muscimol (Theobald et al. 1968; Waser 1967). After oral ingestion, the onset of the inebriation is rather slow, and generally 2-3 hours elapse before the full effects are felt (Chilton 1975). This delayed response has also been reported following ingestion of Amanita pantherina (Ott 1976a). The effects last for 6-8 hours, depending on dose. Effects are characterized by visual distortions, loss of equilibrium, mild muscle twitching (not convulsions, as has erroneously been reported), and altered auditory and visual perception (Chilton 1975; Ott 1976a).
It would appear that muscimol is the psychoactive constituent, and that following ingestion of ibotenic acid, a fraction of the material decarboxylates to muscimol, which then produces the inebriation. After oral ingestion of ibotenic acid, a substantial percentage of the drug is excreted unaltered in the urine, but small amounts of muscimol are also excreted (Chilton, unpublished). This mechanism would potentially explain the Siberian urinary drug recycling practice. After ingestion of the mushroom, the celebrant would excrete substantial amounts of ibotenic acid in his urine. A second user ingesting the urine of the first, would cause some of the ibotenic acid to be decarboxylated to muscimol during digestion, producing inebriation when the muscimol was absorbed; and the bulk of the ibotenic acid would be re-excreted in his urine in turn. Thus a 100 mg dose of ibotenic acid might potentially represent four or five 10-15 mg doses of muscimol, and Steller's 1774 report that one dose of mushrooms could be recycled through four or five persons is certainly feasible. Muscimol itself probably does not play a significant role in urinary drug recycling, since it was found that only a small percentage of injected muscimol was excreted in the urine of mice (Ott et al. 1975a). This hypothesis has yet to be verified quantitatively in human beings, though it has been demonstrated qualitatively in preliminary experiments (Chilton 1979). "
Svampene skulle efter sigende indeholde langt mere muscimol i starten af sesonen.